Early expression of b- and g-subunits of epithelial sodium channel during human airway development
نویسندگان
چکیده
DOMINIQUE GAILLARD,1 JOCELYNE HINNRASKY,1 SYLVIE COSCOY,2 PAUL HOFMAN,3 MICHAEL A. MATTHAY,4 EDITH PUCHELLE,1 AND PASCAL BARBRY2,4 1Institut National de la Santé et de la Recherche Médicale Unité 514, Institut Fédératif de Recherches 53, Centre Hospitalier Universitaire Maison Blanche, 51092 Reims Cedex; 2Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique Unité Propre de Recherche 411, 06560 Sophia Antipolis; 3Institut National de la Santé et de la Recherche Médicale Unité 364, Tour Pasteur Faculté de Médecine, 06107 Nice Cedex 02, France; and 4Cardiovascular Research Institute, University of California, San Francisco, California 94143-0130
منابع مشابه
BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels.
The recently defined DEG/ENaC superfamily of sodium channels includes subunits of the amiloride-sensitive epithelial sodium channel (ENaC) of vertebrate colon, lung, kidney, and tongue, a molluscan FMRFamide-gated channel (FaNaC), and the nematode degenerins, which are suspected mechanosensory channels. We have identified two new members of this superfamily (BNaC1 and BNaC2) in a human brain cD...
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